Association study between a polymorphism at the 3′-untranslated region of CLOCK gene and attention deficit hyperactivity disorder.

Xu X, Breen G, Chen CK, Huang YS, Wu YY, and Asherson P. Behav Brain Funct. 2010 Aug 12;6:48.

The aim of this study was to determine if there was a relationship between attention-deficit hyperactivity disorder (ADHD) and the rs1801260 SNP in clock. A study of two populations (392 children aged 5-15 from the UK and Taiwan) found a positive association between ADHD (as diagnosed via DSM-IV) and the T allele of the rs1801260 SNP on the circadian gene clock.

rs1801260 in clock

Clock rs1801260

NCBI Variation Viewer rs1801260


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